Endocrine Abstracts

Background: The discovery of a thyroid nodule exposes the problem of the possibility of thyroid cancer. The difficulty of management of this situation is the fact that only the histopathological examination can confirm or refute the malignancy. Fine-needle aspiration (FNA) is used as a diagnostic tool to assess thyroid nodules. The purpose of our study is to correlate the clinical, ultasonographic, the FNA results and final pathology to determine the predictors of malignancy o...

Introduction: The therapeutic management of premature ovarian failure (POF) consists of a hormone replacement therapy that must be regular to avoid cardiovascular and bone complications as well as psychological management. The objective of this work was to study complications at 15 years of evolution of 42 tunisian women followed for POF.Patients and methods: It’s a retrospective study of 42 patients followed in the endocrinology department of Souss...

Introduction: Gestational diabetes mellitus (GDM) arises from elevated glycemia during pregnancy, posing risks to both mother and fetus. Managing GDM involves close monitoring and dietary control, with antenatal insulin therapy (AIT). The aim of this study was to evaluate the efficiency of diverse maternal characteristics and biological indicators identified during GDM diagnosis in anticipating the inadequacy of dietary measures and the requirement for AIT to achieve glucose t...

Introduction: Verneuil’s disease, also known as Hidradenitis suppurativa, is a chronic inflammatory dermatosis characterized by recurrent episodes. It’s manifested by painful deep inflammatory nodules, comedones, and scarring in areas rich in apocrine glands. Its prevalence is estimated at 1% of the population. It is influenced by factors such as obesity, smoking, and genetics. We report the case of a patient admitted for diabetes in whom Hidradenitis suppurativa was...

Introduction: The most recent declared pandemic is attributed to COVID-19, caused by the novel coronavirus SARS-CoV-2. The angiotensin-converting enzyme 2, the principal receptor for SARS-CoV-2, exhibits expression in various tissues, prominently within gonadal and hypothalamo-hypophyseal domains. Long COVID, characterized by persistent symptoms post-infection, manifests in certain individuals and includes manifestations associated with the genitourinary system, such as sexual...

Introduction: Macroprolactinemia is a polymeric form of prolactin release that leads to clinically paucisymptomatic presentations. It can be isolated or associated with other causes of hyperprolactinemia. We report the case of macroprolactinemia discovered in a patient being treated for an empty sella turcica.Case report: This concerns a 47-year-old patient, monitored since the age of 31 for moderate idiopathic hyperprolactinemia discovered following bil...

Introduction: Pregnancy induces significant hormonal alterations, potentially affecting thyroid hormones. Our study aimed to assess the prevalence of thyroid dysfunction in pregnant women diagnosed with gestational diabetes Mellitus (GDM).Methods: A descriptive study was conducted, including 197 pregnant women diagnosed with GDM, under the care and monitoring at the Diabetology, Endocrinology department in Farhat Hached university Hospital, Sousse Tunisi...

Introduction: COVID-19 is a viral infection that can affect various endocrine tissues, including the thyroid. In some patients, symptoms may persist after the infection, defined as Long COVID. Given the similarity of some of these symptoms to those encountered in thyroid disorders, we have decided to assess thyroid function in patients previously infected with SARS-CoV-2.Patients & Methods: This was a prospective study conducted from January to Decem...

Introduction: Cushing’s disease (CD) is reported in 60-70% of all patients with Cushing’s syndrome (CS), but occurs only in approximately 33% of the reported CS cases in pregnancy. Nevertheless, despite its rarity, pregnancy in patients with CS can be troublesome because of the risk of maternal-fetal complications.Observation: A 28-year-old female patient was referred to our endocrinology department for a suspected CS with morphological alter...

IntroductionParagangliomas (PGs) are rare tumors arising from sympathetic and parasympathetic paraganglia with an incidence of 15–20%. We report a case of a pre-operative diagnosis of retroperitoneal PGs evoked on anatomic imaging confirmed by biochemical evaluation.ObservationA 55-year-old female was referred to the endocrinology department for investigation of a paroxistic hypertension. For her persona...